Sammanfattning
Originalspråk | engelska |
---|---|
Tidskrift | Scandinavian Journal of Gastroenterology |
Volym | 43 |
Utgåva | 9 |
Sidor (från-till) | 1094-1101 |
Antal sidor | 8 |
ISSN | 0036-5521 |
DOI | |
Status | Publicerad - 2008 |
MoE-publikationstyp | A1 Tidskriftsartikel-refererad |
Vetenskapsgrenar
- 514 Socialvetenskaper
- 414 Jordbruksbioteknologi
- 411 Jordbruks- och skogsvetenskaper
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Unkilned and large amounts of oats in the coeliac disease diet : a randomized, controlled study. / Kemppainen, Tarja A; Heikkinen, Markku T; Ristikankare, Matti K; Kosma, Veli-Matti; Sontag-Strohm, Tuula; Brinck, Outi; Salovaara, Hannu; Julkunen, Risto J.
I: Scandinavian Journal of Gastroenterology, Vol. 43, Nr. 9, 2008, s. 1094-1101.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
TY - JOUR
T1 - Unkilned and large amounts of oats in the coeliac disease diet
T2 - a randomized, controlled study
AU - Kemppainen, Tarja A
AU - Heikkinen, Markku T
AU - Ristikankare, Matti K
AU - Kosma, Veli-Matti
AU - Sontag-Strohm, Tuula
AU - Brinck, Outi
AU - Salovaara, Hannu
AU - Julkunen, Risto J
PY - 2008
Y1 - 2008
N2 - Objective. There is evidence for the long-term safety of oats as part of a gluten-free diet in coeliac disease (CD). Oats is generally processed by kilning, which theoretically may change its antigenic properties and be the reason that it is tolerated by patients with CD. The aim of this study was to investigate the suitability of large amounts of unkilned oats, comparing its use with kilned oats in adult coeliac patients. Material and methods. The study group included 13 men and 19 women with CD in remission. The goal of daily intake of oats was 100 g during one year. These patients using oats as part of their gluten-free diet were randomized to two treatment groups. One group used regular oats and the other unkilned oats. After 6 months the patients changed the treatment groups. Food intake, symptoms, histology of the small intestine and the levels of endomysial antibodies were noted. Results. No marked changes were found in the duodenal biopsies, in the levels of endomysial antibodies or in the well-being of the patients. Compliance with the diet did not change during the follow-up. Conclusions. Large amounts of both unkilned and regular kilned oats are well tolerated by adult patients with CD. Oats is therefore not harmful, even in its unkilned form, which indicates that its antigenic nature is not changed by common industrial food processing in such a way that would prevent the provoking of CD.
AB - Objective. There is evidence for the long-term safety of oats as part of a gluten-free diet in coeliac disease (CD). Oats is generally processed by kilning, which theoretically may change its antigenic properties and be the reason that it is tolerated by patients with CD. The aim of this study was to investigate the suitability of large amounts of unkilned oats, comparing its use with kilned oats in adult coeliac patients. Material and methods. The study group included 13 men and 19 women with CD in remission. The goal of daily intake of oats was 100 g during one year. These patients using oats as part of their gluten-free diet were randomized to two treatment groups. One group used regular oats and the other unkilned oats. After 6 months the patients changed the treatment groups. Food intake, symptoms, histology of the small intestine and the levels of endomysial antibodies were noted. Results. No marked changes were found in the duodenal biopsies, in the levels of endomysial antibodies or in the well-being of the patients. Compliance with the diet did not change during the follow-up. Conclusions. Large amounts of both unkilned and regular kilned oats are well tolerated by adult patients with CD. Oats is therefore not harmful, even in its unkilned form, which indicates that its antigenic nature is not changed by common industrial food processing in such a way that would prevent the provoking of CD.
KW - 514 Sociology
KW - 414 Agricultural biotechnology
KW - 411 Agriculture and forestry
U2 - 10.1080/00365520802014858
DO - 10.1080/00365520802014858
M3 - Article
VL - 43
SP - 1094
EP - 1101
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
SN - 0036-5521
IS - 9
ER -